The Philadelphia Eagles are heading into their international game against the Jacksonville Jaguars with a significantly depleted roster. On the official injury report, the team confirmed that five players have been ruled out for the contest in London.

The list of unavailable players includes high-profile offensive starters: running back Saquon Barkley and wide receiver DeVonta Smith. Additionally, the team will be without new starting center Drew Kendall, wide receiver Hollywood Brown, and safety Marcus Epps.

The absence of these players presents a major challenge for the Eagles' coaching staff as they prepare for the Jaguars. While the team has not provided specific details regarding the nature of each player's injury or the expected duration of their absence, their exclusion from the London trip is definitive. The Eagles will now have to rely on their depth chart to fill these critical positions during Sunday's game. As of now, no further updates have been provided by the organization regarding potential replacements or the long-term outlook for the injured players.