As teams finalize their rosters for the upcoming slate of NFL games, several high-profile players are dealing with injury designations that will impact their team's lineups. Caleb Williams, the rookie quarterback, has been officially ruled out for his team's contest. His absence marks a significant change for the offense as they prepare for kickoff.

In contrast, the status of Los Angeles Rams wide receiver Puka Nacua remains a point of uncertainty. Reports indicate that his participation is not yet guaranteed, leaving his fantasy managers and team coaches waiting for final confirmation closer to game time. Conversely, the situation for quarterback Sam Darnold is clear; he has been cleared to play and is expected to start. These updates are critical for fans and analysts tracking the shifting landscape of player availability across the league this week. As the official inactive lists are finalized, teams will adjust their game plans to account for these personnel changes.